Изучение биологического действия кизила листьев экстракта жидкого

The purpose of this work is to study antimicrobic, diuretic action, acute toxicity of a cornel leaves liquid extract. Cornel leaves liquid extract was obtained by the method of counterflow multistage extraction in the battery of six diffuzors at a phases ratio of 1:2 with the use of 70% ethyl alcohol. The results of the conducted microbiological researches showed that the cornel extract in the primary form, and also in dulutions (up to 1:10) possessed high antimicrobial effect towards coccal flora, enterobacteria, spore forming bacteria and mushrooms which surpasses Hypericum tincture in activity. It can be used to treat some infectious diseases of gastrointestinal tract. Soft diuretic effect of in a dose of 1 ml per 1 kg of weight which is comparable to an action of Lespefril was revealed. The complex of biologically active agents of the cornel extract, at per os application, belongs to a low hazard substances or substances of the 4th class of toxicity. The toxicity of the cornel leaves liquid extract is due to the toxicity of 64% of ethyl alcohol.