The Combination of Area Under the Curve and Percentage Change in Estimated Glomerular Filtration Rate Predicts Long‐term Outcome of Kidney Transplants

The development of surrogate markers for long-term outcomes of kidney transplant (KT) is a focus of attention. We examined the possibility of using a combination of the area under the curve of estimated glomerular filtration rate (eGFR) for 2 years (AUCeGFR2yrs ) and percent change in eGFR between 1 and 2 years after KT (% changeeGFR1/2yr ) as a surrogate marker. We compared the predictive power of death-censored graft failure with various combinations. The combination of >2% vs 1300 vs /=30% decline in eGFR between years 1 and 3 after KT (