Beneficial effect of curcumin isolated from Curcuma longa on exercise-induced hepatocyte apoptosis of rat

The aim of this study was to determine the effect of curcumin isolated from curcuma longa on exercise-induced hepatocyte apoptosis. 24 male Wistar rats were used for the study. The experiment was a 14-day exhaustive exercise. We determined the protein expression of bax and bcl-2 in the hepatic tissues. The results demonstrated that bax and bcl-2 co-regulated the exercise-induced hepatocyte apoptosis. Bax promotes the apoptosis as up-regulated genes, while bcl-2 inhibits apoptosis as down-regulated genes. Curcumin can inhibit exercise-induced hepatocyte apoptosis. The experimental results provided theoretical support for curcumin in the field of sports nutrition.