20（S）-原人参二醇对肝癌间质血管密度和肿瘤细胞增殖活性的影响

To discuss influence of protopanaxdiol to interstitial microvascular density and proliferation activity of liver cancer. To construct liver cancer animal models and the experimental animals are divided into five groups, each group includes ten animals. That is control group, CTX group, protopanaxdiol 25mg/kg, 50mg/kg, 100mg/kg group. After two weeks, all the experimental animals will be killed, we will determine tumor volume and weight, then deal it into tissue spices for immmunohistochemistry. To compare with control group, in protopanaxdiol groups, tumor interstitial microvascular density is lower, and its proliferation activity also lower, its volume and weight is lower distinguishly. It suggests that protopanaxdiol inhibites tumor interstitial microvascular density and its proliferation activity, finally inhibites tumor growth.