Process for preparing formulations spray-dried TMC125.

A process for producing a solid pharmaceutical powder, comprising the steps of: (a) providing a feed mixture of microcrystalline cellulose and a solution of a polimerohidrosoluble and TMC125; (B) spray drying the feed mixture from step (a) to form a solid dispersion of TMC125 and the polymer by introducing the feed mixture as droplets into a spray-drying chamber via an atomizing device.