Analysis of Multivariate Factors for Noninvasive Ventilation In the Patients with Acute Cardiogenic Pulmona-ry Edema

Objective To analyze the multivariate factors associated with failure of applying noninvasive ven-tilation(NIV)in the patients with acute cardiogenic pulmonary edema(ACPE).Methods 65 patients with ACPE re-ceived NIV treatment,and were divided into NIV syccess group and NIV failure group according to the result with NIV therapy.Compared with the exchanges of the relevant parameters before the treatment and in the treatment between these two groups,analysis the alert factors and observational factors of the failure in NIV treatment.Resylts 27 cases in failure on NIV were elders,with acute myocardial infarction,decline on PaCO_2,raise on PH,low on MPA,compared with the success group.In NIV treatment and observing the changes of RR,PaO2,PaCO_2,there is a obviously differ-ence(P<0.05)on the HR improvement in the patients of the success group compared with the patients of the failure group.Conclusion The factors of elder,acute myocardial infarction,decline on PaCO_2,raise on PH,low on MPA could be seemed as the alert factors before the NIV treatment,the efficiency of therapy of NIV could be judged through observing HR,RR,PaO_2,PaCO_2 in NIV treatment. Key words: Noninvasive ventilation; Acute cardiogenic pulmonary edema; Failure; Multivariate factors