Neuroendocrine carcinoma of the larynx

A case of small-cell carcinoma of the larynx was diagnosed in a 65-year-old man whose only symptom was voice change. Two cervical lymph nodes were present. Indirect laryngoscopy demonstrated a smooth-surfaced mass on the lingual face of the epiglottis, which was confirmed by CAT of the larynx and throat. Histological study was consistent with small-cell carcinoma, is a rare neuroendocrine tumor for this site. The therapeutic strategy is described. A bibliographic review was made to clarify reports of these rare tumors using different nomenclature and classifications.