A Study of Fructose-1,6-Diphosphate in Causing Neonatal Hypocacemia

Objective: To observe the blood calcium effect of fructose-1, 6-diphosphate (FDP) injection in treatment of newborn anoxic cardiac muscle harm. Methods: One hundred and fifty-five patients of neonates with anoxic cardiac muscle harm were divided into two groups, 78 cases in the treatment group were treated with routine treatment and FDP, 77 cases of the control group were treated with routine treatment only. Incidence of hypocalcemia, which was determined by blood samples, was compared between the two groups. Results: The incidence of hypocalcemia in FDP group was 64.10%, and that in non-FDP group was 15.58%. It is significant in statistics between the two groups (χ2=38.01, P0.05). And there were also significant differrences in statistics between the two groups in the durations of main clinic symptoms such as convulsion, ecphysesis, vomiting and abdominal distention with values of t respectively amounted to 14.35, 13.83, 14.18 (P0.05). Conclusions: FDP may cause neonatal hypocalcemia, and the duration of its symptoms would be longer.