Anti-angiogenic and anti-inflammatory effects of CD200–CD200R1 axis in oxygen-induced retinopathy mice model

Objective In this study, the expression changes and the potential effects of CD200 and its receptors during the process of retinal neovascularization (RNV) development had been detected, using a classic oxygen-induced retinopathy (OIR) mice model and CD200Fc (a CD200R1 agonist) intravitreal injection.