Release of active forms of oxygen by blood neutrophils of Syrian hamsters with primary and transplanted tumors

: The production of reactive oxygen forms by the blood neutrophils of Syrian hamsters bearing primary or transplantable tumours has been studied by chemiluminescence test. It is demonstrated that at the early developmental stages of spontaneous primary lymphosarcomas, or of certain malignant transplantable tumours of different origin there is a significant decrease in the spontaneous chemiluminescence and an increase in phagocytosis-dependent chemiluminescence of blood neutrophils. Such a decrease in the spontaneous chemiluminescence was not observed in hamsters bearing tumours with the low metastatic activity as well as in animals with abscesses.