Constant change: dynamic regulation of membrane transport by calcium signalling networks keeps plants in tune with their environment

Membrane transport proteins (MTPs) govern the flow of molecules across membranes, and their activities are closely monitored and regulated by cell signaling networks. By continuously adjusting their membrane transport activities, plants can mitigate or buffer the effects of environmental perturbations. Here, we examine the role of calcium signaling networks in the coordinated modulation of membrane transport, placing a special emphasis on potassium transport. Potassium is an exceptionally abundant and mobile ion in plants, and the plant potassium transport network and its regulation have been intensive areas of study for several decades. Studies have underscored the importance of calcium ions in plant environmental responses and the regulation of membrane transport. In reviewing recent advances in our understanding of the coding and decoding of calcium signals in plants, we highlight established and emerging roles of calcium signaling in the coordination of membrane transport, drawing several examples from the CBL-CIPK signaling network. By synthesizing classical studies and recent findings, we aim to provide timely insights on the role of calcium signaling networks in the modulation of membrane transport and its importance in plant environmental responses. This article is protected by copyright. All rights reserved.