Nephrotisches Syndrom bei einem jungen Mann : Drei Biopsien – drei Diagnosen? (Bild und Fall)

This report describes the case of a 24-year-old man who was treated with cyclosporin A for histologically proven focal segmental glomerulosclerosis (FSGS) and remained in stable remission. After 4 years the patient suffered a sudden flare of nephrotic syndrome and two renal biopsies at 1 year follow-up intervals showed different forms of immune complex glomerulonephritis. The patient was diagnosed as having endocarditis lenta and was treated surgically. Over the next few months the nephrotic syndrome improved without the need for further immune modulatory therapy.