Dll4 and Notch signalling couples sprouting angiogenesis and artery formation

Mara E. Pitulescu,Inga Schmidt,Benedetto Daniele Giaimo,Tobiah Antoine,Frank Berkenfeld,Francesca Ferrante,Hongryeol Park,Manuel Ehling,Daniel Biljes,Susana Rocha,Urs H. Langen,Martin Stehling,Takashi Nagasawa,Napoleone Ferrara,Tilman Borggrefe,Ralf H. Adams

Dll4 and Notch signalling couples sprouting angiogenesis and artery formation

2017

Mara E. Pitulescu
Inga Schmidt
Benedetto Daniele Giaimo
Tobiah Antoine
Frank Berkenfeld
Francesca Ferrante
Hongryeol Park
Manuel Ehling
Daniel Biljes
Susana Rocha
Urs H. Langen
Martin Stehling
Takashi Nagasawa
Napoleone Ferrara
Tilman Borggrefe
Ralf H. Adams

Pitulescu et al. and Hasan et al. show that Dll4–Notch signalling in endothelial tip cells regulates angiogenesis through control of artery formation, linking sprouting angiogenesis and artery formation.

Keywords:

Artery
Vasculogenesis
Sprouting angiogenesis
Cell biology
Cell lineage
Angiogenesis
Notch signaling pathway
Biology

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