Monitoring Treatment: Clinical and Programmatic Approach for Drug-Susceptible and Drug-Resistant Tuberculosis

Tuberculosis (TB) treatment management of patients becomes more difficult with increasing drug resistance. Monitoring of TB treatment is therefore of utmost importance to increase the success rate and prevent complications. This chapter provides an overview of the most critical microbiological, clinical and drug-related parameters at the start and during the treatment of tuberculosis. Therapeutic drug monitoring has been recommended in order to further minimize drug-related adverse reactions and optimize treatment response. An approach on how to include personalized management in programmatic treatment is included.