Application of autologous pericardial patch in repairing simple ventricular septal defect of infants

Objective To investigate the outcomes of autologous pericardial patch treated by glutaraldehyde in repairing simple ventricular septal defect of infants.Methods Four hundred and three infants with ventricular septal defect were selected,and the ventricular septal defect was repaired with autologous pericardial patch treated by glutaraldehyde.Results No patient experienced hemolysis,infection,three-degree atrioventricular block and aneurysmal dilation after operation.Residual shunt occurred in 29 patients.Patients were followed up for 1.5 months to 2 years,the residual shunt disappeared in 26 patients,and that of the other 3 patients was not healed,while none needed a second operation.There was no significant difference in the rates of residual shunt among patients with different ages and different types of ventricular septal defect(P0.05).Conclusion Autologous pericardial patch treated by glutaraldehyde is a good material for repairing simple ventricular septal defect of infants.