Evidence for the Role of the Cecal Microbiome in Maintenance of Immune Regulation and Homeostasis.

Objective (s):Our objective was to investigate alterations in the cecal microbial composition during the development of type 1 diabetes (T1D) with or without IgM therapy, and correlate these alterations with the corresponding immune profile.Methods:(1) Female nonobese diabetic (NOD) mice treated wit