Plasma cell-free DNA profiling of PI3K/Akt pathway aberrations in two multi-institutional independent metastatic castration-resistant prostate cancer (mCRPC) cohorts.

Edmond M. Kwan,Chao Dai,Heidi Fettke,Christine Hauser,Patricia Bukczynska,Nicole Ng,Siavash Foroughi,Lisa-Jane K Graham,Kate L. Mahon,Winston Tan,Amy T. Wang,Zhixin Zhao,Tiantian Zheng,Kemin Zhou,Jianjun Yu,Peter Du,Lisa G. Horvath,Shidong Jia,Manish Kohli,Arun Azad

Plasma cell-free DNA profiling of PI3K/Akt pathway aberrations in two multi-institutional independent metastatic castration-resistant prostate cancer (mCRPC) cohorts.

2021

159Background: Tumour tissue from metastatic castration-resistant prostate cancer (mCRPC) harbors frequent copy number variations (CNVs) in the phosphatidylinositol-3-kinase (PI3K)/Akt-signaling pa...

Keywords:

Plasma cell
Prostate cancer
Cancer research
free dna
castration resistant
Copy-number variation
PI3K/AKT/mTOR pathway
Tumour tissue
Medicine

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