Effect of bradykinin on TGF-β1-induced retinal pigment epithelial cell proliferation and extracellular matrix secretion

Wenting Cai,Qingquan Wei,Qingyu Liu,Chengda Ren,Junling Liu,Ruiling Zhang,Mengmei He,Qianyi Wang,Yaru Du,Jing Yu

Effect of bradykinin on TGF-β1-induced retinal pigment epithelial cell proliferation and extracellular matrix secretion

2016

Wenting Cai
Qingquan Wei
Qingyu Liu
Chengda Ren
Junling Liu
Ruiling Zhang
Mengmei He
Qianyi Wang
Yaru Du
Jing Yu

Background To evaluate the effect of bradykinin (BK) on TGF-β1-induced retinal pigment epithelial (RPE) cell proliferation and extracellular matrix secretion and to elucidate the relationship between BK and the Erk/Akt signaling pathway.

Keywords:

Cell biology
Bradykinin
Akt/PKB signaling pathway
MAPK/ERK pathway
Surgery
Secretion
Endocrinology
Retinal
Extracellular matrix
Signal transduction
Internal medicine
Medicine
Retinal pigment epithelium
Molecular biology
Fibronectin
Cell growth
Protein kinase B

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