Multiobjective optimization of semibatch reactive crystallization processes

The determination of the optimal feed profiles for a reactive crystallizer is an important dynamic optimization problem, as the feed profiles offer a significant control over the quality of the product crystals. Crystallization processes typically have multiple performance objectives and optimization using different objective functions leads to significantly different optimal operating conditions. Therefore, a multiobjective approach is more appropriate for optimization of these processes. The potential for multiobjective optimization approach is demonstrated for semibatch reactive crystallization processes. The multiobjective approach usually gives rise to a set of optimal solutions, largely known as Pareto-optimal solutions. The Pareto-optimal solutions can help the designer visualize the trade-offs between different objectives, and select an appropriate operating condition for the process. A well known multiobjective evolutionary algorithm, the elitist nondominated sorting genetic algorithm, has been adapted to illustrate the potential for the multiobjective optimization approach. © 2007 American Institute of Chemical Engineers AIChE J, 2007