Detrimental hemodynamic and inflammatory effects of microparticles

Microparticles (MPs) are membrane vesicles with procoagulant and proinflammatory properties released during cell activation and might be potentially involved in the pathophysiology of septic shock [1,2]. The present study was designed to assess the effects of MPs from septic origin on systemic hemodynamics as well as on the inflammatory, oxidative and nitrosative stresses.