Myeloid Progenitor Cells in the Premetastatic Lung Promote Metastases by Inducing Mesenchymal to Epithelial Transition

Dingcheng Gao,Natasha Joshi,Hyejin Choi,Seongho Ryu,Mary Hahn,Raul Catena,Helen Sadik,Pedram Argani,Patrick L. Wagner,Linda T. Vahdat,Jeffrey L. Port,Brendon M. Stiles,Saraswati Sukumar,Nasser K. Altorki,Shahin Rafii,Vivek Mittal

Myeloid Progenitor Cells in the Premetastatic Lung Promote Metastases by Inducing Mesenchymal to Epithelial Transition

2012

Dingcheng Gao
Natasha Joshi
Hyejin Choi
Seongho Ryu
Mary Hahn
Raul Catena
Helen Sadik
Pedram Argani
Patrick L. Wagner
Linda T. Vahdat
Jeffrey L. Port
Brendon M. Stiles
Saraswati Sukumar
Nasser K. Altorki
Shahin Rafii
Vivek Mittal

Bone marrow cells attracted to the lungs of breast cancer patients interact with metastatic tumor cells to stimulate mesenchymal to epithelial transition, thereby promoting tumor progression.

Keywords:

Bone marrow
Mesenchymal stem cell
Myeloid Progenitor Cells
Breast cancer
Tumor progression
Immunology
Lung
Pathology
Medicine
metastatic tumor

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