1575-P: Health-Related Quality of Life in Patients with Type 2 Diabetes: A Case-Control Study

Background: Health-related quality of life (HR-QOL) assessment is considered an important aspect of outcome in diabetes treatment. Objective: We investigated the association between QOL and clinical characteristics of patients with diabetes. Methods: Among 571 patients with type 2 diabetes and 958 healthy control subjects, the target subjects who were matched by age and sex were divided into two groups (504 in the diabetic group and 504 in the nondiabetic group). The 36-Item Short Form Health Survey questionnaire (SF-36) was used to evaluate HR-QOL. Unpaired Student’s tests and Pearson’s chi-square test were used for statistical analyses. Results: (1) Scores of physical functioning, role physical (physical and mental), general health, and social functioning were significantly lower in the diabetic group than in the nondiabetic group (P Conclusions: QOL was significantly decreased in patients with type 2 diabetes compared with that in healthy subjects. QOL of patients with diabetic complications was significantly decreased; thus, such conditions should be taken into account when providing treatment to patients with diabetes. Disclosure H. Murakami: None. T. Fujita: None. M. Murabayashi: None. S. Mizushiri: None. S. Osonoi: None. Y. Matsuhashi: None. M. Daimon: None.