An Introduction of Two-Step K-means Clustering Applied to Microarray Data

Long gene sequences and their products have been studied by many methods. The use of DNA(Deoxyribonucleic acid) microarray technology has resulted in an enormous amount of data, which has been difficult to analyze using typical research methods. This paper proposes that mass data be analyzed using division clustering with the K-means clustering algorithm. To demonstrate the superiority of the proposed method, it was used to analyze the microarray data from rice DNA. The results were compared to those of the existing K-meansmethod establishing that the proposed method is more useful in spite of the effective reduction of performance time.