Analysis and Comparison of Salivary L-Fucose and HSP 70 in Oral Potentially Malignant Disorders and Oral Cancer

The aim of this study was to assess the level of salivary L-Fucose and Heat Shock Protein 70 in subjects in subjects with Oral Potentially Malignant Disorders and Oral Cancer.\ Method & Results: The study was done among 90 subjects - 30 healthy subjects, 30 subjects with Oral Potentially Malignant Disorders and 30 subjects with Oral Cancer. Saliva samples were collected and the levels of L-Fucose and HSP-70 were determined. Data obtained was analyzed using ANOVA test for the comparison between the groups. Post hoc tukey`s analysis was used for comparing the study groups to the control group.The levels of L-Fucose and HSP-70 in saliva were increased significantly in subjects with Oral potentially malignant disorders and Oral Cancer in comparison to the healthy subjects. Conclusion: Elevated levels of HSP 70 and L-fucose in saliva in oral potentially malignant disorders and oral cancer indicate their usefulness as biomarkers for early prediction.