Isolation of the Phrenic Nerve to Suppress Diaphragmatic Contraction Induced by Cardiac Resynchronization

Phrenic Nerve Isolation in Cardiac Resynchronization. Left phrenic nerve stimulation is a well-known complication of cardiac resynchronization therapy (CRT). We report a case where electronic or anatomical repositioning of the left ventricular (LV) electrode (within the coronary sinus tributaries) was not feasible/effective. Surgical graft interpositioning was performed to successfully isolate the phrenic nerve from the previously implanted coronary sinus epicardial LV lead. (J Cardiovasc Electrophysiol, Vol. 23, pp. 778-780, July 2012)