Pénfigo Vulgar y Lupus Eritematoso Sistémico. Reporte de caso

Systemic Lupus Erythematosus (SLE) is an autoimmune, multisystemic and episodic disease, characterized by generalized vascular inflammation and connective tissue, and by the presence of antinuclear antibodies (ANA) and anti-double-stranded DNA antibodies. The term is a rare blistering disease of autoimmune etiology that affects the skin and mucous membranes. Define a group of autoimmune diseases of the skin characterized by the presence of immunoglobulin G (IgG) directed to the surface of keratinocytes and blisters due to an evaluation (intercellular separation). Female patient of 16 years of age, with history of presentation, edema in right knee, hands and feet accompanied by arthralgias of one year of evolution. In addition, dificulty for walking of 3 days of evolution. It presented bullous lesions in confluent oral mucosa and upper lip and spread to surrounding skin. The metacarpophalangeal joints of the hands were edematized, painful, with mild deformity and functional limitation. The initial blisters located on the face and lower extremities extended to the lower limbs, accompanied by bilateral palmar erythema. He was diagnosed with Pemphigus vulgaris and Systemic Lupus Erythematosus. The latter, for presenting laboratory criteria compatible with SLE: leukopenia, positive ANA, nephropathy and arthritis. Drying treatment with prednisone 50 mg orally every day (1 mg / kg / day). Keywords Autoimmune Diseases, Lupus Erythematosus, Pemphigus