Exploring β-CD grafted GO nanocomposites with an encapsulated fluorescent dye duly optimized by molecular docking for better applications

Abstract Here, we have designed and synthesized β-cyclodextrin grafted Graphene Oxide based fluorescent probe with encapsulated fluorescent dye. The nanocomposites were characterized by several spectroscopic methods such as FTIR, DLS, zeta potential, UV–vis and fluorescence spectroscopy. Thermal gravimetric analysis (TGA) was employed to account for thermal stability of β-CD grafted graphene oxide nanocomposites. Nile blue molecules are well encapsulated into the cyclodextrin cavity and embedded on the surface of Graphene Oxide sheet. Molecular Docking study helps us to understand the feasibility of encapsulation process of fluorescent dye inside our synthesized nanocomposites. Various physicochemical properties like UV–vis and fluorescence spectra of composite in different solvent and photophysical properties like fluorescence quantum yield, molar extinction coefficient, stokes shift have been calculated.