In situ laser-induced synthesis of copper‑silver microcomposite for enzyme-free d-glucose and l-alanine sensing

Abstract In this work, we reported in situ laser-induced synthesis of sensor-active copper‑silver microcomposite. This bimetallic microelectrode exhibits highly developed surface area and good electrical conductivity, and can be successfully used for glucose and alanine sensing demonstrating decent sensitivity (31,000 μА cm−2 mМ−1 for d -glucose and 11,177 μА cm−2 mМ−1 for l -alanine) and low limit of detection (2.8 μM for d -glucose and 0.83 μM for l -alanine). High sensor activity and good electrochemical characteristics of the synthesized material can be associated with the eutectic type of the Cu-Ag system. The implemented technique is quite useful for fabrication of new promising small size sensors for enzymeless determination of different biological analytes.