New antimycobacterial 2,3-dihydro-1-alkylindole-2-thiones.

A series of 2,3-dihydroindole-2-thiones was evaluated forin vitro antimycobacterial activity againstMycobacterium tuberculosis, M. kansasii, M. fortuitum, two strains ofM. intracellulare and three strains ofM. avium. 2,3-Dihydro-1-methyl-2-thioxoindole-3-one and 2,3-dihydro-1-butyl-2-thioxoindole-3-one were the most active substances against potentially pathogenic strains, being more active than isoniazide.