EFFECT OF TOTAL ECDYSTEROID PREPARATION FROM Silene viridiflora ON THE IMMUNE STATE OF EXPERIMENTAL ANIMALS UNDER NORMAL AND SECONDARY IMMUNODEFICIENCY CONDITIONS

The isolation of total ecdysteroids from Silene viridiflora is described. The preparation acts as an effective immunomodulator in normal animals (mice, 18 – 20 g) and in mice with secondary immunodeficiency developed under irradiation, acute toxic hepatitis, and prolonged physical load conditions. The immunomodulating activity of total ecdysteroids from S. viridiflora is comparable with that of the known immunity stimulator T-activin, a preparation of polypeptide nature from cattle thymus.