Effective Assignment of α2,3/α2,6-Sialic Acid Isomers by LC-MS/MS-Based Glycoproteomics

Christian Pett,Waqas Nasir,Carina Sihlbom,Britt-Marie Olsson,Vanessa Caixeta,Manuel Schorlemer,René P. Zahedi,Göran Larson,Jonas Nilsson,Ulrika Westerlind

Effective Assignment of α2,3/α2,6-Sialic Acid Isomers by LC-MS/MS-Based Glycoproteomics

2018

Christian Pett
Waqas Nasir
Carina Sihlbom
Britt-Marie Olsson
Vanessa Caixeta
Manuel Schorlemer
René P. Zahedi
Göran Larson
Jonas Nilsson
Ulrika Westerlind

Abstract Distinct structural changes of the α2,3/α2,6-sialic acid glycosidic linkages on glycoproteins are of importance in cancer biology, inflammatory diseases, and virus tropism. Current glycopr ...

Keywords:

Glycosidic bond
Organic chemistry
Glycoprotein
Glycopeptide
Liquid chromatography–mass spectrometry
Glycoproteomics
Mass spectrometry
Biochemistry
Sialic acid
Glycosylation
Chemistry
lc ms ms

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