New insights in swine model of ventricular tachycardia using quantitative myocardial tissue characterization

Background Ventricular tachycardia (VT) is often responsible for sudden cardiac death and is generally triggers by the presence of reentry circuits related to a chronic myocardial scar. We have recently developed a novel swine model of VT, where sustained monomorphic reentrant VT can be induced in all animals. This new model offers exciting opportunities for better understanding the underlying substrate of VT, as well as for the development of new mapping and ablation strategies. In this study, we sought to provide in-vivo tissue characterization of this model using myocardial tissue characterization techniques of T1, T2 and high-resolution LGE.