Simultaneous Determination of Two Synthetic Dyes Erytrosine and Sunset Yellow in a Pharmaceutical Syrup By First Derivative Visible Spectrophotometry

ABSTRACT. A rapid first derivative spectrophotometric method for simultaneous determination of two synthetic dyes, erytrosine (E 127) and sunset yellow (E 110), in a mixture is proposed. The procedure does not require any separation step. The method was applied for determining the two compounds in a pharmaceutical syrup. Good linearity, accuracy, precision and selectivity were found, and the method is proposed for routine quality control purposes.