Phase I clinical trial of lenalidomide in combination with 5-fluorouracil, leucovorin, and oxaliplatin in patients with advanced cancer

Rabih Said,Yang Ye,David S. Hong,Aung Naing,G. S. Falchook,Siqing Fu,Jennifer J. Wheler,Sarina Anne Piha-Paul,Apostolia Maria Tsimberidou

Phase I clinical trial of lenalidomide in combination with 5-fluorouracil, leucovorin, and oxaliplatin in patients with advanced cancer

2016

Rabih Said
Yang Ye
David S. Hong
Aung Naing
G. S. Falchook
Siqing Fu
Jennifer J. Wheler
Sarina Anne Piha-Paul
Apostolia Maria Tsimberidou

Purpose Lenalidomide has synergistic anticancer effects when used with chemotherapy. We conducted a phase I study of lenalidomide in combination with FOLFOX (5-fluorouracil, leucovorin, and oxaliplatin) in patients with advanced cancer.

Keywords:

Fluorouracil
Cancer
Phases of clinical research
FOLFOX
Lenalidomide
Pharmacology
Oxaliplatin
Chemotherapy
Cancer research
Surgery
Medicine
advanced cancer
Oncology
Internal medicine
in patient

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