TRATAMIENTO DE LA ENFERMEDAD HEPÁTICA GRASA NO ALCOHÓLICA

Nonalcoholic fatty liver disease (NAFLD) is a fatty disease of the liver that is not associated with alcohol. Its prevalence increases along with the epidemic of obesity and type 2 diabetes, and the risk of suffering a more aggressive liver disease is greater with the consequent increase in cirrhosis, hepatocellular carcinoma and cardiovascular disease (CVD). The ectopic accumulation of fat is associated with high-fat diets and high energy density, hyperglycemia and insulin resistance that lead to the suppression of hepatic glucose production and decreased glucose uptake by the skeletal muscle which promotes the lipogenesis of novo and generates a vicious circle that favors even more steatosis.