ОПАСНОСТЬ ПЕРЕДАЧИ ВИРУСОВ ГЕПАТИТОВ В И С С КРОВЬЮ ДОНОРОВ

The residual risk of transfusion infection by hepatitis B virus (HBV) and C (HCV) in Russia is several tens of times higher than in the USA. In developed countries for many years there is widely used the testing the blood samples by means of the polymerase chain reaction (PCR) of individual donors and mini-pools. This is an advantageous economic decision, because it reduces the cost of preparing of blood components. The aim of the study was to analyze the proper level of the viral safety. Molecular markers of viruses were detected in plasma samples of seronegative donors (n = 33,799) in pools out of 6. The levels of viral molecular markers were calculated in 72 positive samples: 21 – HBV DNA, 51 – HCV RNA. There were investigated prepared experimentally 17 plasma pools contained HBV DNA, HCV RNA positive specimen. Commercial reagent kits were used.