Segmental allergen challenge increases levels of airway follistatin-like 1 in patients with asthma

Marina Miller,Stephane Esnault,Richard C. Kurten,Elizabeth A. Kelly,Andrew Beppu,S.C. Das,Peter Rosenthal,Joe W. Ramsdell,Michael Croft,Bruce L. Zuraw,Nizar N. Jarjour,Qutayba Hamid,David H. Broide

Segmental allergen challenge increases levels of airway follistatin-like 1 in patients with asthma

2016

Marina Miller
Stephane Esnault
Richard C. Kurten
Elizabeth A. Kelly
Andrew Beppu
S.C. Das
Peter Rosenthal
Joe W. Ramsdell
Michael Croft
Bruce L. Zuraw
Nizar N. Jarjour
Qutayba Hamid
David H. Broide

Segmental allergen challenge induced increased levels of bronchoalveolar (BAL) follistatin like 1 (FSTL1). BAL macrophages both expressed FSTL1, and could be induced by FSTL1 to express MMP9 suggesting a potential role of FSTL1 in remodeling.

Keywords:

Immunology
Allergen
Case-control study
Airway
Young adult
Asthma
Follistatin-Related Proteins
Follistatin
Medicine
allergen challenge
in patient

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