Ruthenium(II)/Chiral Broensted Acid Co‐Catalyzed Enantioselective Four‐Component Reaction/Cascade Aza‐Michael Addition for Efficient Construction of 1,3,4‐Tetrasubstituted Tetrahydroisoquinolines.

2014

A four-component Mannich/cascade aza-Michael reaction using a ruthenium complex with a chiral Broensted acid is developed.

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