Grubbs catalysts in intramolecular carbene C(sp3)–H insertion reactions from α-diazoesters

Grubbs catalysts are described as a useful alternative to promote intramolecular carbene C–H insertion from α-diazoesters. Moreover, no competition arises from the possible metathesis reactions on substrates bearing alkene and alkyne moieties. DFT calculations were also carried out to gain insight into the reaction mechanism involved in these transformations.