The sensitivity of interferon-gamma release assays is not compromised in tuberculosis patients with diabetes.

Setting The sensitivity of the IFN-γ release assays (IGRAs) to detect Mycobacterium tuberculosis infection or disease may be affected by immune derangement in diabetes. Since millions of type 2 diabetes patients are at risk for tuberculosis worldwide, it is important to determine if the sensitivity of IGRAs is compromised in this vulnerable population.