sublingual tablets low dose of opioid analgesics and preparation process

2007 
A sublingual tablet comprising less than 20 mg / tablet of a suitable opioid analgesic for sublingual administration, comprising a compressible diluent directly as neutral cores, wherein said neutral cores are granules being essentially spherical comprising sucrose and starch, and wherein said neutral cores are coated with at least one active layer comprising less than 5% by weight of the neutral core of said suitable opioid analgesic for sublingual administration.
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