A study of various heparin salts

: The methods for preparing acid and neutral Na+, K+, Ca2+ and Mg2+ salts of individual heparin fractions were devised. One of the fractions contains 3 (HP = 3) and another 4 (HP = 4) sulfate groups per dimer of the macromolecule of both the polymers. Infrared spectra of the salts were obtained. It was shown that acid salts of HP = 3 (with the exception of Mg2+ salt) and HP = 4 form intermolecular hydrogen bonds. The structure of the infrared spectra of HP = 3 and HP = 4 salts depends, to a significant degree, on the cation nature.