Effect of nicotine and cigarette smoke on an experimental model of intraepithelial lesions and pancreatic adenocarcinoma induced by 7,12-dimethylbenzanthracene in mice.

Vivian Pierri Bersch,Alessandro Bersch Osvaldt,Maria Isabel Albano Edelweiss,Rita de Cássia Schumacher,Luiz Roberto Rigo Wendt,Laís Pilau de Abreu,Carla Brauner Blom,Gabriela Pilau de Abreu,Leonardo Gazzi Costa,Pedro Piccinini,Luiz Rohde

Effect of nicotine and cigarette smoke on an experimental model of intraepithelial lesions and pancreatic adenocarcinoma induced by 7,12-dimethylbenzanthracene in mice.

2009

Vivian Pierri Bersch
Alessandro Bersch Osvaldt
Maria Isabel Albano Edelweiss
Rita de Cássia Schumacher
Luiz Roberto Rigo Wendt
Laís Pilau de Abreu
Carla Brauner Blom
Gabriela Pilau de Abreu
Leonardo Gazzi Costa
Pedro Piccinini
Luiz Rohde

Objectives:To evaluate the effects of nicotine and cigarette smoke exposure on mice submitted to 7,12-dimethylbenzanthracene (DMBA) model of pancreatic carcinogenesis.Methods:One hundred fourteen male mice were divided into the DMBA-n and DMBA-s groups: the DMBA-n group was given 2 mg/kg per dose of

Keywords:

Endocrinology
Carcinoma in situ
Internal medicine
Nicotine
DMBA
Smoke
Cocarcinogenesis
Carcinogen
Diabetes mellitus
Adenocarcinoma
Biology
cigarette smoke exposure
experimental model
cigarette smoke
male mice
Chemistry

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations