The virus-inducted structures in RNA virus infected macrophages

Beside nonspecific character pathology of cells infected by virus, within its the typical for viral infection changes can be defined as virus-inducted structures — the viroplasts, polyribosomal filaments, microfibrils and others. The system of mononuclear phagocytes phylogenically belongs to the most ancient system of immunity. Experimental evidences suggest that macrophages play the important role in resistance to viral infection [1]. In this study, we tested the ultrastructure of infected RNA enveloped (Hantavirus, caused hemorrhagic fever with renal syndrome, and Tick Borne encephalitis virus, TBEV) and nonenveloped (poliovirus, enteroviruses ECHO11, Coxsackie B1 and 71) viruses primary macrophages of mice.