Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction

Krishna M. Boini,Tahir Hussain,Pin-Lan Li,Sai S Koka

Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction

2017

Krishna M. Boini
Tahir Hussain
Pin-Lan Li
Sai S Koka

Background/Aim: Plasma trimethylamine-N-oxide (TMAO), a product of intestinal microbial metabolism of dietary phosphatidylcholine has been recently associated wit

Keywords:

Phosphatidylcholine
Biochemistry
Inflammasome
Diabetes mellitus
Endothelial dysfunction
NLRP3 inflammasome activation
Trimethylamine N-oxide
Microbial metabolism
Biology
In vivo
Confocal microscopy
Cell biology
Colocalization
Western blot

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