AgAsF6 as safe alternative to AgClO4 for generating cationic zirconocene species: Utilities in lewis acid-promoted selective CC bond forming reactions

Abstract For generating cationic zirconocene species that are useful for organic synthesis, AgAsF 6 proved to be an efficient catalyst that serves as a safe alternative to AgClO 4 . Scope and limitation is discussed on this new catalyst in the processes including (1) alkyl/alkenyl transfer reaction from organozirconocene chloride to aldehyde, (2) two- and four-carbon homologation of aldehyde, (3) dual synthetic methods of 1,3-dienes from aldehydes/ketones via 1,3-bimetallic species, and (4) three-component alkylative cycloaddition via o -quinodimethane species.