Bone tumours of the clavicle: Histopathological, anatomical and epidemiological analysis of 113 cases

Abstract Backround This retrospective study aimed to determine the frequency of bone tumours of the clavicle and their histopathological, anatomical and epidermiological characteristics in a large case series. Methods The records of 327 lesions of the clavicle collected from 1976 to 2018 in our bone tumour registry and institute of pathology were reviewed. Following data were evaluated: age, gender, side, radiological assessment, tumour location within the clavicle, and histopathological findings. Results Bone tumours were detected in 113 patients with a mean age of 40 years. The lateral third of the clavicle was most frequently involved. Analysis revealed 22 benign, 31 intermediate, and 60 malignant tumours. Eosinophilic granuloma was the most commonly found neoplasm, followed by bone metastases, Plasma cell myeloma, Ewing sarcoma, and Osteosarcoma. 53% of the tumours were malignant. Mean age was 51 years in the malignant tumour group and 28 years in patients with a benign/intermediate lesion (p Conclusions Bone tumours of the clavicle seem to have different histopathological and epidermiological characteristics than bone tumours at other sites. A high index of suspicion should be maintained when evaluating patients with clavicular lesions due to the high incidence of malignancy, especially in patients with increased age.