Синтез, антирадикальная и антибактериальная активность производных 4-(3’,4’-дигидроксифенил)тиазола
2015
A series of dihydroxyphenylthiazoles have been synthesized by the reaction of 4-(chloroacetyl)cathehol with thioamide derivatives. The obtained compounds show antiradical activity with respect to 2,2’-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) radical cation. The antibacterial activity have been studied against P. aeruginosa , C. albicans , S. epidermidis , and S. aureus . The synthesized compounds belong to the fourth class of toxicity.
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