P263 Relationship between comorbidity and quality of life in the patient with chronic obstructive pulmonary disease

Objectives To describe the profile of the patient with Chronic Obstructive Pulmonary Disease (COPD) in a health center, to know the comorbidity and its relationship with the quality of life. Methods Cross sectional study. Of the patients included in the Clinical Care Program for patients with COPD at the Health Center (N=443), all patients who had been evaluated for quality of life in 2018 by their doctor through the COPD Assessment Test (CAT) were studied (n=129). Variables analyzed: age, sex, body mass index (BMI), smoking habit, GOLD obstructive pattern, degree of obstruction, dyspnea according to the Medical Research Council (MCR), quality of life with CAT, number and type of exacerbations and comorbidities, treatment of COPD, total drugs. Descriptive statistics, bivariate analysis. Results Age 72.02±9.46 (male 78.29%). Ex-smoker 62.02%, active smoker 37.98%, BMI 27.64±5.05. Correct diagnosis with spirometry 85%. According obstructive pattern GOLD 1: 25 (19.84%); GOLD 2: 64 (50.8%); GOLD 3: 31 (24.6%) GOLD 4: 6 (4.76%). Dyspnea MRC 1.7±0.96, with significant dyspnea (≥2) 51%. Quality of life with CAT 13.5±8.2, with a significant impact (>10) 58.9%. The patients had 129 exacerbations: mild 21 (17.7%), moderate 87 (70.7%), and severe with admission 15 (12.1%). Average comorbidities: 4.17 (2.59%). Average of drugs: 8.24±4.28. The most commonly drugs for COPD were LAMA (87) 67.4%; LABA (66) 51.16%; Inhaled corticosteroids (50) 38.76%; SABA 38 (29.46%); SAMA 28 (21.71%). Comorbidity: hypertension (69%), arthrosis (42%), dyslipidemia (38%), diabetes (36%), obesity (32%), gastrointestinal disorder 30%, heart failure (24%), ischemic heart disease (23%), arrhythmia (20%), peripheral arterial disease (19.4%), sleep apnea syndrome (18.6%), anxiety (13%), osteoporosis (11.6%), hyperuricemia (11.6%), depression (11.5%), cerebrovascular disease (10.8%), lung cancer (0.01%). The GOLD grade (P Conclusions The profile of our patient COPD is a male ex-smoker, overweight, polymedicated, with comorbidity, being the most frequent: hypertension, osteoarthritis, dyslipidemia and diabetes, with a moderate obstruction to airflow, significant dyspnea and an average impact on his quality of life. Addressing comorbidity in COPD patients can improve quality of life.