Assessment of Orocoecal Transit Time by Means of a Hydrogen (H2) Breath Test as Compared with a Radiologic Control Method

The definition of the orocoecal transit time by means of the hydrogen (H2) breath test is not unequivocal. In this study the orocoecal transit time as measured with an H2 breath test was compared with that obtained with a radiologic method. Two definitions of orocoecal transit time by the H2 breath test were evaluated: A) the time from eating to the first of three consecutively rising H2 values, and B) the interval to H2 values 50% above ‘small-bowel level’. Transit times measured in accordance with both definitions were closely correlated to that obtained with the radiologic method (A, r = 0.84; B, r = 0.90; for both, p < 0.001), but transit time measured by definition A gave shorter values than the radiologic method (p < 0.05). The mean transit time in patients with constipation was significantly longer than that in normal subjects and patients with functional diarrhoea (p < 0.05). There was a significant correlation between the difference in transit time measured with the H2 breath test and the radiolo...